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Organic Mechanisms and Synthesis

General

Prefix

CHEM

Course Number

455

Course Level

Undergraduate

Department/Unit(s)

College/School

College of Science and Engineering

Description

Advanced organic chemistry involving key mechanisms and reactions; strategies and tactics of complex organic syntheses. Lab.

Prerequisites

Credits

Min

4

Max

4

Repeatable

No

Goals and Diversity

MN Goal Course

No

Cultural Diversity

No

Learning Outcomes

Outcome

Use organic structure to predict chemical reactivity.

Outcome

Apply retrosynthetic and synthetic methods in the building of molecules.

Outcome

Use software to draw and model compounds.

Outcome

Locate and interpret synthetic organic chemistry journal articles.

Outcome

Complete a multi-step sequence toward the synthesis of a natural product.

Outcome

Run, work-up, purify, and characterize organic reactions.

Outcome

Collect and interpret spectroscopic data.

Outcome

Prepare publication-quality research results.

Course Outline

Course Outline

General organic chemistry review. 10% Advanced reactions - oxidations and reductions. 10% Advanced reactions - alkene reactions. 10% Advanced reactions - carbon-carbon bond forming reactions. 20% Stereochemistry review and utilization of chemistry drawing and modeling programs. 10% Methods of asymmetric synthesis - chiral auxiliaries. 15% Methods of asymmetric synthesis - chiral reagents and catalysts. 10% Synthetic sequence project. 15%

Dependencies

Programs

CHEM455 is a completion requirement for: