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NMDT 423. Nuclear Medicine Chemistry

Credits: 1-3
Department: Nuclear Medicine Technology
Description: The radiopharmacology and chemistry of radionuclides used in the clinical laboratory.
Semester Offered:
  • Fall
  • Spring
  • Summer
Grading Method: ABCDF
Additional Information: Must be in clinical internship.

Student Learning Outcomes

1. Illustrate various methods of isotope production.
2. Explain the various methods used for producing artificial radionuclides, with an emphasis on the production of the radionuclides used in the nuclear medicine department.
3. Identify the different types of impurities that can be present in technetium kit preparations and how to test for each of them.
4. Explain the physics, construction, and operational aspects of a radionuclide generator (especially with respect to a Mo-99/Tc-99m generator).
5. Identify appropriate quality control procedures for Tc-99m eluate and radiopharmaceuticals, including radionuclide purity, radiochemical purity, and chemical impurities.
6. Discuss the production and characteristics of positron emitters and positron-labeled radiopharmaceuticals.
7. Explain the Food and Drug Administration and US Pharmacopeia control of pharmaceuticals and radiopharmaceuticals.

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